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Search Results for " menin-mll interaction "

20

Compounds

Cat No. Product Name Synonyms Targets
T28036 MI-2-2 MI22,MI 2 2 Histone Methyltransferase
MI-2-2 is an inhibitor of bivalent protein-protein interaction between menin and MLL with an IC50 of 46 nM. MI-2-2 binds to menin with Kd of 22 nM.
T2643 MI-3 Menin-MLL Inhibitor,Menin-MLL inhibitor 3,MI 3 Apoptosis , Epigenetic Reader Domain , Histone Methyltransferase
MI-3 (Menin-MLL Inhibitor) (Menin-MLL Inhibitor) is an effective inhibitor of Menin-MLL interaction (IC50: 648 nM).
T9399 Menin-MLL inhibitor 20 Epigenetic Reader Domain , Histone Methyltransferase
Menin-MLL inhibitor 20 is an irreversible inhibitor of menin-MLL interaction with antitumor activities.
T2649 Menin-MLL inhibitor MI-2 Menin-MLL Inhibitor,MI2,MI-2,Menin-MLL inhibitor 2,MI 2 Apoptosis , Epigenetic Reader Domain , Histone Methyltransferase
Menin-MLL inhibitor MI-2 (MI2) is a potent menin-MLL interaction inhibitor with IC50 of 446 nM.
TQ0069 MI-503 Epigenetic Reader Domain , Histone Methyltransferase
MI-503 is a highly effective and orally bioavailable inhibitor of the menin-mLL interaction.
T11925 M‑89 Epigenetic Reader Domain , Histone Methyltransferase
M-89, a highly potent and specific inhibitor of the menin-mixed lineage leukemia (Menin-MLL) protein-protein interaction, exhibits a Kd of 1.4 nM for menin binding. This compound holds potential for treating MLL leukemia...
T16072 MI-538 Epigenetic Reader Domain , Histone Methyltransferase
MI-538 is an interaction between menin and MLL fusion proteins inhibitor(IC50 of 21 nM).
TQ0058 MI-463 Epigenetic Reader Domain , Histone Methyltransferase
MI-463 is a potent and orally bioavailable inhibitor of the menin-mLL interaction (IC50: 15.3 nM).
T39585 Ziftomenib KO-539 Histone Methyltransferase
Ziftomenib (KO-539) is an inhibitor of menin-MLL interaction with antitumor activity and can be used to study leukemia.
T13336 VTP50469 Apoptosis , Epigenetic Reader Domain , Histone Methyltransferase
VTP50469 is a highly selective and orally active inhibitor of Menin-MLL interaction( Ki: 104 pM) and has potently anti-leukemia activity.
T12002 Menin-MLL inhibitor 4 Others
Menin-MLL inhibitor 4 has antitumor activity.Menin-MLL inhibitor 4 is an inhibitor of Menin- MLL (mixed-lineage leukemia protein) interaction .
T72135 (1s,4s)-Menin-MLL inhibitor-23
(1s,4s)-Menin-MLL Inhibitor-23, an enantiomer of Menin-MLL Inhibitor-23 (Example 99A), functions as an inhibitor of the menin-MLL interaction [1].
T22978 MI-2 (hydrochloride) Others
MI-2 (Menin-MLL Inhibitor) is an effective menin-MLL interaction inhibitor (IC50: 446 ± 28 nM).
T24484 ML399 VU-0516340,VU 0516340,ML-399,VU0516340,ML 399
ML399 is the menin-- MLL interaction inhibitor that acts by demonstrating strong and selective effects in MLL leukemia cells and validating specific mechanism of action.
T24472 MIV-6R MIV6R,VU05163101,VU0516310-1,VU0516310 1,MIV 6R
MIV-6R is an inhibitor of the menin- MLL interaction that acts by demonstrating strong and selective effects in MLL leukemia cells and validating specific mechanisms of action.
T61735 MI-1
MI-1 inhibits Menin-MLL interaction with an IC 50 of 1.9 μM [1].
T13336L VTP50469 fumarate Others
VTP50469 fumarate is a highly selective and orally active inhibitor of Menin-MLL interaction (Ki: 104 pM), and has potently anti-leukemia activity.
T27134 DCYM21 DC YM 21,DC-YM21,DCYM-21,DC_YM21,DC YM21
DCYM21 is an inhibitor of menin-MLL interaction. DCYM21 demonstrates potent and selective blockage of proliferation and induces both cell cycle arrest and differentiation of leukemia cells harboring MLL translocations.
T79117 Menin-MLL inhibitor 27 Epigenetic Reader Domain
Menin-MLL inhibitor 27 effectively inhibits the interaction between Menin and MLL, serving as a potential tool in cancer research, particularly for acute myeloid leukemia (AML) [1].
T39938 M-1211
M 1121 is a covalent and orally active inhibitor of the menin-MLL interaction capable of achieving complete and persistent tumor regression.

Compounds

MI-2-2
T28036
Synonym: MI22,MI 2 2
Target: Histone Methyltransferase
MI-3
T2643
Synonym: Menin-MLL Inhibitor,Menin-MLL inhibitor 3,MI 3
Target: Apoptosis, Epigenetic Reader Domain, Histone Methyltransferase
Menin-MLL inhibitor 20
T9399
Synonym:
Target: Epigenetic Reader Domain, Histone Methyltransferase
Menin-MLL inhibitor MI-2
T2649
Synonym: Menin-MLL Inhibitor,MI2,MI-2,Menin-MLL inhibitor 2,MI 2
Target: Apoptosis, Epigenetic Reader Domain, Histone Methyltransferase
MI-503
TQ0069
Synonym:
Target: Epigenetic Reader Domain, Histone Methyltransferase
M‑89
T11925
Synonym:
Target: Epigenetic Reader Domain, Histone Methyltransferase
MI-538
T16072
Synonym:
Target: Epigenetic Reader Domain, Histone Methyltransferase
MI-463
TQ0058
Synonym:
Target: Epigenetic Reader Domain, Histone Methyltransferase
Ziftomenib
T39585
Synonym: KO-539
Target: Histone Methyltransferase
VTP50469
T13336
Synonym:
Target: Apoptosis, Epigenetic Reader Domain, Histone Methyltransferase
Menin-MLL inhibitor 4
T12002
Synonym:
Target: Others
(1s,4s)-Menin-MLL inhibitor-23
T72135
Synonym:
Target:
MI-2 (hydrochloride)
T22978
Synonym:
Target: Others
ML399
T24484
Synonym: VU-0516340,VU 0516340,ML-399,VU0516340,ML 399
Target:
MIV-6R
T24472
Synonym: MIV6R,VU05163101,VU0516310-1,VU0516310 1,MIV 6R
Target:
MI-1
T61735
Synonym:
Target:
VTP50469 fumarate
T13336L
Synonym:
Target: Others
DCYM21
T27134
Synonym: DC YM 21,DC-YM21,DCYM-21,DC_YM21,DC YM21
Target:
Menin-MLL inhibitor 27
T79117
Synonym:
Target: Epigenetic Reader Domain
M-1211
T39938
Synonym:
Target:
1 2
TargetMol